Ethical Toxicity Studies: Promoting Safe Practices

Use of animals for experimentation in education, training & research.
An integral part of the pharmacology education at medical colleges, pharmacy, veterinary institutes.
An essential part of basic research & preclinical drug discovery process.
Animal models are used to test possibilities that would be difficult or impossible to test using the target species
It is mandatory to do extensive toxicological studies in animals before the candidate drug gets approval for clinical trials in humans.

The Centre has CPCSEA approval for experiments of small animals.
We have our own Institutional Animal Ethics Committee Regulated by CPCSEA New Delhi for ethical clearance of toxicity study. (Reg. no. 1938/PO/Rc/S/17/CPCSEA)

Acute toxicity study on rats and mice through injectable and oral dosage form (7 – 14 days period according to the CDSCO Schedule Y requirements of Drugs and Cosmetic Act, New Amendment and OECD guidelines, NDCT Rules 2019).
Sub acute/ Sub Chronic toxicity study on rats and rabbits through injectable and oral dosage form (28 days period.
Chronic Toxicity Study on rats, mice and rabbits (90 - 120 days period.
Dermal, Skin Sensitization, Irritation Toxicity Study on Rabbits &Rats (patch test for 72 hours or subchronic for 28 days.
Photo-Allergy Or Dermal Photo-Toxicity Study In Guinea Pig.
Ophthalmic Toxicity Study on Rabbits and rats.